Does FILGRASTIM Cause Osteonecrosis? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Osteonecrosis have been filed in association with FILGRASTIM (NYPOZI txid). This represents 0.1% of all adverse event reports for FILGRASTIM.
16
Reports of Osteonecrosis with FILGRASTIM
0.1%
of all FILGRASTIM reports
1
Deaths
3
Hospitalizations
How Dangerous Is Osteonecrosis From FILGRASTIM?
Of the 16 reports, 1 (6.3%) resulted in death, 3 (18.8%) required hospitalization.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FILGRASTIM. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does FILGRASTIM Cause?
Off label use (1,930)
Febrile neutropenia (1,570)
Neutropenia (1,431)
Death (1,213)
Pyrexia (1,085)
Diarrhoea (739)
Nausea (718)
Bone pain (706)
Thrombocytopenia (697)
Anaemia (626)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which FILGRASTIM Alternatives Have Lower Osteonecrosis Risk?
FILGRASTIM vs FILGRASTIM-AAFI
FILGRASTIM vs FILGRASTIM-SNDZ
FILGRASTIM vs FINASTERIDE
FILGRASTIM vs FINASTERIDE\TAMSULOSIN
FILGRASTIM vs FINERENONE