Does FLUOROURACIL Cause Cachexia? 93 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 93 reports of Cachexia have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.2% of all adverse event reports for FLUOROURACIL.
93
Reports of Cachexia with FLUOROURACIL
0.2%
of all FLUOROURACIL reports
43
Deaths
56
Hospitalizations
How Dangerous Is Cachexia From FLUOROURACIL?
Of the 93 reports, 43 (46.2%) resulted in death, 56 (60.2%) required hospitalization, and 3 (3.2%) were considered life-threatening.
Is Cachexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 93 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Cachexia?
NIVOLUMAB (314)
METHOTREXATE (134)
PREDNISONE (102)
CARBIDOPA\LEVODOPA (96)
PACLITAXEL (94)
MYCOPHENOLATE MOFETIL (90)
TACROLIMUS (85)
ADALIMUMAB (84)
CYCLOPHOSPHAMIDE (83)
OCTREOTIDE (81)
Which FLUOROURACIL Alternatives Have Lower Cachexia Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE