Cachexia: Which Medications Cause It? (3,473 Reports Across 337 Drugs)
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Cachexia has been reported as an adverse event with 337 different drugs in the FDA's FAERS database, with 3,473 total reports. 1,137 of these reports resulted in death.The drugs most commonly associated with Cachexia are NIVOLUMAB, METHOTREXATE, and PREDNISONE.
3,473
Total Reports
337
Drugs Involved
1,137
Deaths
1,704
Hospitalizations
60.7 yrs
Average Patient Age
46.4% / 53.6%
Female / Male
Which Drugs Cause Cachexia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NIVOLUMAB | 314 | 0.4% | 50 | 70 | 12 |
| METHOTREXATE | 134 | 0.1% | 34 | 62 | 34 |
| PREDNISONE | 102 | 0.1% | 24 | 60 | 15 |
| CARBIDOPA\LEVODOPA | 96 | 0.2% | 50 | 59 | 2 |
| PACLITAXEL | 94 | 0.1% | 41 | 45 | 2 |
| FLUOROURACIL | 93 | 0.2% | 43 | 56 | 3 |
| MYCOPHENOLATE MOFETIL | 90 | 0.1% | 26 | 64 | 9 |
| TACROLIMUS | 85 | 0.1% | 30 | 56 | 11 |
| ADALIMUMAB | 84 | 0.0% | 14 | 62 | 9 |
| CYCLOPHOSPHAMIDE | 83 | 0.1% | 33 | 44 | 24 |
| OCTREOTIDE | 81 | 0.3% | 38 | 49 | 5 |
| PEMBROLIZUMAB | 81 | 0.1% | 31 | 52 | 10 |
| RITUXIMAB | 81 | 0.1% | 36 | 44 | 6 |
| DEXAMETHASONE | 79 | 0.1% | 46 | 55 | 15 |
| BEVACIZUMAB | 75 | 0.1% | 43 | 30 | 0 |
| CARBOPLATIN | 75 | 0.1% | 22 | 50 | 3 |
| OXALIPLATIN | 75 | 0.1% | 34 | 48 | 2 |
| ASPIRIN | 73 | 0.1% | 4 | 52 | 2 |
| DOXORUBICIN | 68 | 0.1% | 25 | 37 | 14 |
| METHYLPREDNISOLONE | 67 | 0.1% | 19 | 53 | 11 |