Does METHOTREXATE Cause Cachexia? 134 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 134 reports of Cachexia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
134
Reports of Cachexia with METHOTREXATE
0.1%
of all METHOTREXATE reports
34
Deaths
62
Hospitalizations
How Dangerous Is Cachexia From METHOTREXATE?
Of the 134 reports, 34 (25.4%) resulted in death, 62 (46.3%) required hospitalization, and 34 (25.4%) were considered life-threatening.
Is Cachexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 134 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Cachexia?
NIVOLUMAB (314)
PREDNISONE (102)
CARBIDOPA\LEVODOPA (96)
PACLITAXEL (94)
FLUOROURACIL (93)
MYCOPHENOLATE MOFETIL (90)
TACROLIMUS (85)
ADALIMUMAB (84)
CYCLOPHOSPHAMIDE (83)
OCTREOTIDE (81)
Which METHOTREXATE Alternatives Have Lower Cachexia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA