Does FLUOROURACIL Cause Clostridium difficile infection? 85 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 85 reports of Clostridium difficile infection have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.2% of all adverse event reports for FLUOROURACIL.
85
Reports of Clostridium difficile infection with FLUOROURACIL
0.2%
of all FLUOROURACIL reports
15
Deaths
51
Hospitalizations
How Dangerous Is Clostridium difficile infection From FLUOROURACIL?
Of the 85 reports, 15 (17.6%) resulted in death, 51 (60.0%) required hospitalization, and 5 (5.9%) were considered life-threatening.
Is Clostridium difficile infection Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 85 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Clostridium difficile infection?
ADALIMUMAB (1,502)
INFLIXIMAB (1,419)
VEDOLIZUMAB (1,130)
LENALIDOMIDE (814)
VANCOMYCIN (743)
METRONIDAZOLE (619)
PREDNISONE (618)
METHOTREXATE (588)
RITUXIMAB (532)
CIPROFLOXACIN (508)
Which FLUOROURACIL Alternatives Have Lower Clostridium difficile infection Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE