Does FLUOROURACIL Cause Constipation? 740 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 740 reports of Constipation have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 1.4% of all adverse event reports for FLUOROURACIL.
740
Reports of Constipation with FLUOROURACIL
1.4%
of all FLUOROURACIL reports
68
Deaths
359
Hospitalizations
How Dangerous Is Constipation From FLUOROURACIL?
Of the 740 reports, 68 (9.2%) resulted in death, 359 (48.5%) required hospitalization, and 22 (3.0%) were considered life-threatening.
Is Constipation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 740 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which FLUOROURACIL Alternatives Have Lower Constipation Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE