Does FLUOROURACIL Cause Hypothyroidism? 100 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 100 reports of Hypothyroidism have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.2% of all adverse event reports for FLUOROURACIL.
100
Reports of Hypothyroidism with FLUOROURACIL
0.2%
of all FLUOROURACIL reports
6
Deaths
18
Hospitalizations
How Dangerous Is Hypothyroidism From FLUOROURACIL?
Of the 100 reports, 6 (6.0%) resulted in death, 18 (18.0%) required hospitalization, and 3 (3.0%) were considered life-threatening.
Is Hypothyroidism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 100 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Hypothyroidism?
PEMBROLIZUMAB (2,326)
LEVOTHYROXINE (2,107)
NIVOLUMAB (1,939)
LENVATINIB (1,375)
ATEZOLIZUMAB (881)
ALBUTEROL (877)
CARBOPLATIN (830)
IPILIMUMAB (770)
AMIODARONE (764)
PREDNISONE (739)
Which FLUOROURACIL Alternatives Have Lower Hypothyroidism Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE