Does FLUOROURACIL Cause Skin hyperpigmentation? 53 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 53 reports of Skin hyperpigmentation have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.1% of all adverse event reports for FLUOROURACIL.
53
Reports of Skin hyperpigmentation with FLUOROURACIL
0.1%
of all FLUOROURACIL reports
3
Deaths
12
Hospitalizations
How Dangerous Is Skin hyperpigmentation From FLUOROURACIL?
Of the 53 reports, 3 (5.7%) resulted in death, 12 (22.6%) required hospitalization, and 2 (3.8%) were considered life-threatening.
Is Skin hyperpigmentation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 53 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Skin hyperpigmentation?
ADAPALENE (2,811)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (2,277)
BIMATOPROST (189)
AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OXYBENZONE (182)
DUPILUMAB (177)
MINOCYCLINE (144)
LENALIDOMIDE (142)
METHOTREXATE (142)
CAPECITABINE (136)
COLLAGENASE CLOSTRIDIUM HISTOLYTICUM-AAES (120)
Which FLUOROURACIL Alternatives Have Lower Skin hyperpigmentation Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE