Does GEFITINIB Cause Hepatic failure? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Hepatic failure have been filed in association with GEFITINIB (Gefitinib). This represents 0.2% of all adverse event reports for GEFITINIB.
11
Reports of Hepatic failure with GEFITINIB
0.2%
of all GEFITINIB reports
5
Deaths
5
Hospitalizations
How Dangerous Is Hepatic failure From GEFITINIB?
Of the 11 reports, 5 (45.5%) resulted in death, 5 (45.5%) required hospitalization, and 1 (9.1%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GEFITINIB. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does GEFITINIB Cause?
Malignant neoplasm progression (1,651)
Drug resistance (1,228)
Death (590)
Diarrhoea (393)
Rash (318)
Metastases to central nervous system (306)
Acquired gene mutation (250)
Disease progression (244)
Drug ineffective (197)
Off label use (166)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which GEFITINIB Alternatives Have Lower Hepatic failure Risk?
GEFITINIB vs GELATIN
GEFITINIB vs GEMCITABINE
GEFITINIB vs GEMCITABINE\GEMCITABINE
GEFITINIB vs GEMFIBROZIL
GEFITINIB vs GEMTUZUMAB OZOGAMICIN