Does HYDROCHLOROTHIAZIDE Cause Encephalopathy? 53 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 53 reports of Encephalopathy have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.3% of all adverse event reports for HYDROCHLOROTHIAZIDE.
53
Reports of Encephalopathy with HYDROCHLOROTHIAZIDE
0.3%
of all HYDROCHLOROTHIAZIDE reports
3
Deaths
46
Hospitalizations
How Dangerous Is Encephalopathy From HYDROCHLOROTHIAZIDE?
Of the 53 reports, 3 (5.7%) resulted in death, 46 (86.8%) required hospitalization, and 6 (11.3%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 53 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Encephalopathy Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL