Does IBRUTINIB Cause Encephalopathy? 69 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 69 reports of Encephalopathy have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
69
Reports of Encephalopathy with IBRUTINIB
0.1%
of all IBRUTINIB reports
35
Deaths
58
Hospitalizations
How Dangerous Is Encephalopathy From IBRUTINIB?
Of the 69 reports, 35 (50.7%) resulted in death, 58 (84.1%) required hospitalization, and 13 (18.8%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 69 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which IBRUTINIB Alternatives Have Lower Encephalopathy Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE