Does IBRUTINIB Cause Hepatic failure? 74 Reports in FDA Database

Q: Does IBRUTINIB cause Hepatic failure?

74 reports of Hepatic failure have been filed with the FDA for IBRUTINIB, representing 0.1% of all IBRUTINIB adverse event reports.

Q: How dangerous is Hepatic failure from IBRUTINIB?

Of 74 reports, 44 (59.5%) resulted in death and 44 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 74 reports of Hepatic failure have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.

Reports of Hepatic failure with IBRUTINIB

0.1%

of all IBRUTINIB reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From IBRUTINIB?

Of the 74 reports, 44 (59.5%) resulted in death, 44 (59.5%) required hospitalization, and 17 (23.0%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for IBRUTINIB.

What Other Side Effects Does IBRUTINIB Cause?

Death (8,007) Off label use (5,446) Fatigue (4,479) Diarrhoea (3,903) Atrial fibrillation (3,671) Pneumonia (3,015) Incorrect dose administered (2,752) Contusion (2,712) Fall (2,375) Asthenia (2,200)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which IBRUTINIB Alternatives Have Lower Hepatic failure Risk?

IBRUTINIB vs IBUPROFEN IBRUTINIB vs IBUPROFEN LYSINE IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT IBRUTINIB vs IBUPROFEN\IBUPROFEN IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE

IBRUTINIB Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure IBRUTINIB Demographics