Does IBRUTINIB Cause Hypercalcaemia? 101 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 101 reports of Hypercalcaemia have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
101
Reports of Hypercalcaemia with IBRUTINIB
0.1%
of all IBRUTINIB reports
27
Deaths
76
Hospitalizations
How Dangerous Is Hypercalcaemia From IBRUTINIB?
Of the 101 reports, 27 (26.7%) resulted in death, 76 (75.2%) required hospitalization, and 6 (5.9%) were considered life-threatening.
Is Hypercalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 101 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Hypercalcaemia?
RITUXIMAB (857)
METHOTREXATE (803)
ADALIMUMAB (663)
TOCILIZUMAB (618)
ABATACEPT (612)
ETANERCEPT (602)
DENOSUMAB (599)
ALENDRONATE (594)
INFLIXIMAB (594)
LEFLUNOMIDE (585)
Which IBRUTINIB Alternatives Have Lower Hypercalcaemia Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE