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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does IBRUTINIB Cause Osteonecrosis? 38 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 38 reports of Osteonecrosis have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.

38
Reports of Osteonecrosis with IBRUTINIB
0.1%
of all IBRUTINIB reports
3
Deaths
17
Hospitalizations

How Dangerous Is Osteonecrosis From IBRUTINIB?

Of the 38 reports, 3 (7.9%) resulted in death, 17 (44.7%) required hospitalization, and 1 (2.6%) were considered life-threatening.

Is Osteonecrosis Listed in the Official Label?

Yes, Osteonecrosis is listed as a known adverse reaction in the official FDA drug label for IBRUTINIB.

What Other Side Effects Does IBRUTINIB Cause?

Death (8,007) Off label use (5,446) Fatigue (4,479) Diarrhoea (3,903) Atrial fibrillation (3,671) Pneumonia (3,015) Incorrect dose administered (2,752) Contusion (2,712) Fall (2,375) Asthenia (2,200)

What Other Drugs Cause Osteonecrosis?

EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935) TENOFOVIR DISOPROXIL (7,182) EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338) COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081) EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492) PREDNISONE (779) PREDNISOLONE (711) DENOSUMAB (567) METHOTREXATE (563) DEXAMETHASONE (531)

Which IBRUTINIB Alternatives Have Lower Osteonecrosis Risk?

IBRUTINIB vs IBUPROFEN IBRUTINIB vs IBUPROFEN LYSINE IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT IBRUTINIB vs IBUPROFEN\IBUPROFEN IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE

Related Pages

IBRUTINIB Full Profile All Osteonecrosis Reports All Drugs Causing Osteonecrosis IBRUTINIB Demographics