Does IBUPROFEN Cause Hepatic failure? 281 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 281 reports of Hepatic failure have been filed in association with IBUPROFEN (equate ibuprofen). This represents 0.3% of all adverse event reports for IBUPROFEN.
281
Reports of Hepatic failure with IBUPROFEN
0.3%
of all IBUPROFEN reports
91
Deaths
207
Hospitalizations
How Dangerous Is Hepatic failure From IBUPROFEN?
Of the 281 reports, 91 (32.4%) resulted in death, 207 (73.7%) required hospitalization, and 75 (26.7%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBUPROFEN. However, 281 reports have been filed with the FAERS database.
What Other Side Effects Does IBUPROFEN Cause?
Drug ineffective (9,352)
Drug hypersensitivity (5,269)
Nausea (4,129)
Vomiting (4,116)
Acute kidney injury (3,639)
Product use in unapproved indication (3,596)
Toxicity to various agents (3,584)
Off label use (3,556)
Intentional overdose (3,185)
Headache (3,010)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which IBUPROFEN Alternatives Have Lower Hepatic failure Risk?
IBUPROFEN vs IBUPROFEN LYSINE
IBUPROFEN vs IBUPROFEN UNKNOWN PRODUCT
IBUPROFEN vs IBUPROFEN\IBUPROFEN
IBUPROFEN vs IBUPROFEN\PHENYLEPHRINE
IBUPROFEN vs IBUPROFEN\PSEUDOEPHEDRINE