Does IBUPROFEN Cause Skin necrosis? 184 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 184 reports of Skin necrosis have been filed in association with IBUPROFEN (equate ibuprofen). This represents 0.2% of all adverse event reports for IBUPROFEN.
184
Reports of Skin necrosis with IBUPROFEN
0.2%
of all IBUPROFEN reports
1
Deaths
168
Hospitalizations
How Dangerous Is Skin necrosis From IBUPROFEN?
Of the 184 reports, 1 (0.5%) resulted in death, 168 (91.3%) required hospitalization, and 3 (1.6%) were considered life-threatening.
Is Skin necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBUPROFEN. However, 184 reports have been filed with the FAERS database.
What Other Side Effects Does IBUPROFEN Cause?
Drug ineffective (9,352)
Drug hypersensitivity (5,269)
Nausea (4,129)
Vomiting (4,116)
Acute kidney injury (3,639)
Product use in unapproved indication (3,596)
Toxicity to various agents (3,584)
Off label use (3,556)
Intentional overdose (3,185)
Headache (3,010)
What Other Drugs Cause Skin necrosis?
METHOTREXATE (620)
ADALIMUMAB (576)
RITUXIMAB (565)
TOCILIZUMAB (530)
ABATACEPT (528)
LEFLUNOMIDE (525)
ETANERCEPT (493)
INFLIXIMAB (491)
HYDROXYCHLOROQUINE (482)
CODEINE (481)
Which IBUPROFEN Alternatives Have Lower Skin necrosis Risk?
IBUPROFEN vs IBUPROFEN LYSINE
IBUPROFEN vs IBUPROFEN UNKNOWN PRODUCT
IBUPROFEN vs IBUPROFEN\IBUPROFEN
IBUPROFEN vs IBUPROFEN\PHENYLEPHRINE
IBUPROFEN vs IBUPROFEN\PSEUDOEPHEDRINE