Does IMATINIB Cause Splenomegaly? 216 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 216 reports of Splenomegaly have been filed in association with IMATINIB (Imatinib). This represents 0.5% of all adverse event reports for IMATINIB.
216
Reports of Splenomegaly with IMATINIB
0.5%
of all IMATINIB reports
63
Deaths
81
Hospitalizations
How Dangerous Is Splenomegaly From IMATINIB?
Of the 216 reports, 63 (29.2%) resulted in death, 81 (37.5%) required hospitalization, and 18 (8.3%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IMATINIB. However, 216 reports have been filed with the FAERS database.
What Other Side Effects Does IMATINIB Cause?
Death (9,708)
Drug ineffective (2,628)
Nausea (2,379)
Diarrhoea (2,203)
Fatigue (1,810)
Malignant neoplasm progression (1,716)
Vomiting (1,599)
Malaise (1,361)
Drug intolerance (1,354)
Drug resistance (1,293)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
VENETOCLAX (211)
Which IMATINIB Alternatives Have Lower Splenomegaly Risk?
IMATINIB vs IMBRUVICA
IMATINIB vs IMDEVIMAB
IMATINIB vs IMEGLIMIN
IMATINIB vs IMETELSTAT
IMATINIB vs IMIDAPRIL