Does RITUXIMAB Cause Splenomegaly? 326 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 326 reports of Splenomegaly have been filed in association with RITUXIMAB (Rituxan). This represents 0.2% of all adverse event reports for RITUXIMAB.
326
Reports of Splenomegaly with RITUXIMAB
0.2%
of all RITUXIMAB reports
80
Deaths
107
Hospitalizations
How Dangerous Is Splenomegaly From RITUXIMAB?
Of the 326 reports, 80 (24.5%) resulted in death, 107 (32.8%) required hospitalization, and 14 (4.3%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RITUXIMAB. However, 326 reports have been filed with the FAERS database.
What Other Side Effects Does RITUXIMAB Cause?
Off label use (39,751)
Drug ineffective (32,186)
Rheumatoid arthritis (19,850)
Pain (16,675)
Fatigue (15,602)
Arthralgia (12,529)
Rash (12,102)
Drug intolerance (11,876)
Infusion related reaction (11,871)
Joint swelling (11,170)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
VENETOCLAX (211)
Which RITUXIMAB Alternatives Have Lower Splenomegaly Risk?
RITUXIMAB vs RITUXIMAB-ABBS
RITUXIMAB vs RITUXIMAB-ARRX
RITUXIMAB vs RITUXIMAB-PVVR
RITUXIMAB vs RIVAROXABAN
RITUXIMAB vs RIVASTIGMINE