Does IMIPENEM Cause Aplasia? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Aplasia have been filed in association with IMIPENEM. This represents 0.7% of all adverse event reports for IMIPENEM.
13
Reports of Aplasia with IMIPENEM
0.7%
of all IMIPENEM reports
9
Deaths
13
Hospitalizations
How Dangerous Is Aplasia From IMIPENEM?
Of the 13 reports, 9 (69.2%) resulted in death, 13 (100.0%) required hospitalization, and 9 (69.2%) were considered life-threatening.
Is Aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IMIPENEM. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does IMIPENEM Cause?
Drug ineffective (351)
Off label use (202)
Condition aggravated (138)
Vomiting (137)
Drug resistance (117)
Nausea (111)
Dyspnoea (97)
Diarrhoea (90)
Pyrexia (90)
Product use in unapproved indication (85)
What Other Drugs Cause Aplasia?
CYTARABINE (229)
ETOPOSIDE (217)
CYCLOPHOSPHAMIDE (213)
METHOTREXATE (199)
VINCRISTINE (167)
DOXORUBICIN (144)
CARBOPLATIN (136)
DEXAMETHASONE (129)
RITUXIMAB (98)
IFOSFAMIDE (88)
Which IMIPENEM Alternatives Have Lower Aplasia Risk?
IMIPENEM vs IMIPRAMINE
IMIPENEM vs IMIQUIMOD
IMIPENEM vs IMITREX
IMIPENEM vs IMMUNE GLOBULIN NOS
IMIPENEM vs IMPLANON