Does IMIPENEM Cause Hepatic failure? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Hepatic failure have been filed in association with IMIPENEM. This represents 0.5% of all adverse event reports for IMIPENEM.
10
Reports of Hepatic failure with IMIPENEM
0.5%
of all IMIPENEM reports
9
Deaths
8
Hospitalizations
How Dangerous Is Hepatic failure From IMIPENEM?
Of the 10 reports, 9 (90.0%) resulted in death, 8 (80.0%) required hospitalization, and 4 (40.0%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IMIPENEM. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does IMIPENEM Cause?
Drug ineffective (351)
Off label use (202)
Condition aggravated (138)
Vomiting (137)
Drug resistance (117)
Nausea (111)
Dyspnoea (97)
Diarrhoea (90)
Pyrexia (90)
Product use in unapproved indication (85)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which IMIPENEM Alternatives Have Lower Hepatic failure Risk?
IMIPENEM vs IMIPRAMINE
IMIPENEM vs IMIQUIMOD
IMIPENEM vs IMITREX
IMIPENEM vs IMMUNE GLOBULIN NOS
IMIPENEM vs IMPLANON