Does INFLIXIMAB Cause Osteonecrosis? 145 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 145 reports of Osteonecrosis have been filed in association with INFLIXIMAB (Renflexis). This represents 0.1% of all adverse event reports for INFLIXIMAB.
145
Reports of Osteonecrosis with INFLIXIMAB
0.1%
of all INFLIXIMAB reports
14
Deaths
53
Hospitalizations
How Dangerous Is Osteonecrosis From INFLIXIMAB?
Of the 145 reports, 14 (9.7%) resulted in death, 53 (36.6%) required hospitalization, and 1 (0.7%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for INFLIXIMAB. However, 145 reports have been filed with the FAERS database.
What Other Side Effects Does INFLIXIMAB Cause?
Off label use (34,801)
Drug ineffective (33,738)
Condition aggravated (16,616)
Rheumatoid arthritis (16,251)
Pain (15,061)
Fatigue (13,473)
Arthralgia (13,441)
Infusion related reaction (12,946)
Product use issue (12,752)
Drug intolerance (11,173)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which INFLIXIMAB Alternatives Have Lower Osteonecrosis Risk?
INFLIXIMAB vs INFLIXIMAB-ABDA
INFLIXIMAB vs INFLIXIMAB-AXXQ
INFLIXIMAB vs INFLIXIMAB-DYYB
INFLIXIMAB vs INFLIXIMAB-QBTX
INFLIXIMAB vs INFLIXIMAB, RECOMBINANT