Does IRINOTECAN Cause Bone marrow failure? 332 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 332 reports of Bone marrow failure have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 1.2% of all adverse event reports for IRINOTECAN.
332
Reports of Bone marrow failure with IRINOTECAN
1.2%
of all IRINOTECAN reports
48
Deaths
90
Hospitalizations
How Dangerous Is Bone marrow failure From IRINOTECAN?
Of the 332 reports, 48 (14.5%) resulted in death, 90 (27.1%) required hospitalization, and 49 (14.8%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 332 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which IRINOTECAN Alternatives Have Lower Bone marrow failure Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE