Does IRINOTECAN Cause Constipation? 466 Reports in FDA Database

Q: Does IRINOTECAN cause Constipation?

466 reports of Constipation have been filed with the FDA for IRINOTECAN, representing 1.7% of all IRINOTECAN adverse event reports.

Q: How dangerous is Constipation from IRINOTECAN?

Of 466 reports, 43 (9.2%) resulted in death and 210 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 466 reports of Constipation have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 1.7% of all adverse event reports for IRINOTECAN.

466

Reports of Constipation with IRINOTECAN

1.7%

of all IRINOTECAN reports

Deaths

210

Hospitalizations

How Dangerous Is Constipation From IRINOTECAN?

Of the 466 reports, 43 (9.2%) resulted in death, 210 (45.1%) required hospitalization, and 5 (1.1%) were considered life-threatening.

Is Constipation Listed in the Official Label?

Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for IRINOTECAN.

What Other Side Effects Does IRINOTECAN Cause?

Diarrhoea (4,157) Neutropenia (2,533) Nausea (2,374) Disease progression (2,018) Off label use (2,018) Vomiting (1,944) Fatigue (1,515) Febrile neutropenia (1,357) Anaemia (1,231) Thrombocytopenia (1,214)

What Other Drugs Cause Constipation?

LENALIDOMIDE (9,635) NIRAPARIB (4,128) ADALIMUMAB (4,063) SEMAGLUTIDE (4,036) TIRZEPATIDE (3,417) ERENUMAB-AOOE (3,104) MORPHINE (2,979) OXYCODONE (2,747) PALBOCICLIB (2,705) POMALIDOMIDE (2,374)

Which IRINOTECAN Alternatives Have Lower Constipation Risk?

IRINOTECAN vs IRON IRINOTECAN vs IRON DEXTRAN IRINOTECAN vs IRON ISOMALTOSIDE 1000 IRINOTECAN vs IRON POLYMALTOSE IRINOTECAN vs IRON SUCROSE

IRINOTECAN Full Profile All Constipation Reports All Drugs Causing Constipation IRINOTECAN Demographics