Does IRINOTECAN Cause Haematotoxicity? 249 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 249 reports of Haematotoxicity have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.9% of all adverse event reports for IRINOTECAN.
249
Reports of Haematotoxicity with IRINOTECAN
0.9%
of all IRINOTECAN reports
39
Deaths
28
Hospitalizations
How Dangerous Is Haematotoxicity From IRINOTECAN?
Of the 249 reports, 39 (15.7%) resulted in death, 28 (11.2%) required hospitalization, and 28 (11.2%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 249 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
METHOTREXATE (799)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
Which IRINOTECAN Alternatives Have Lower Haematotoxicity Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE