Does IRINOTECAN Cause Hepatic encephalopathy? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hepatic encephalopathy have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
27
Reports of Hepatic encephalopathy with IRINOTECAN
0.1%
of all IRINOTECAN reports
12
Deaths
19
Hospitalizations
How Dangerous Is Hepatic encephalopathy From IRINOTECAN?
Of the 27 reports, 12 (44.4%) resulted in death, 19 (70.4%) required hospitalization, and 2 (7.4%) were considered life-threatening.
Is Hepatic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Hepatic encephalopathy?
ACETAMINOPHEN (562)
RIBAVIRIN (512)
LENVATINIB (502)
RIFAXIMIN (462)
SOFOSBUVIR (360)
BEVACIZUMAB (210)
LEDIPASVIR\SOFOSBUVIR (180)
ATEZOLIZUMAB (178)
SORAFENIB (169)
DACLATASVIR (165)
Which IRINOTECAN Alternatives Have Lower Hepatic encephalopathy Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE