Does IRINOTECAN Cause Pruritus? 188 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 188 reports of Pruritus have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.7% of all adverse event reports for IRINOTECAN.
188
Reports of Pruritus with IRINOTECAN
0.7%
of all IRINOTECAN reports
5
Deaths
30
Hospitalizations
How Dangerous Is Pruritus From IRINOTECAN?
Of the 188 reports, 5 (2.7%) resulted in death, 30 (16.0%) required hospitalization, and 5 (2.7%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 188 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which IRINOTECAN Alternatives Have Lower Pruritus Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE