Does IRINOTECAN Cause Renal impairment? 135 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 135 reports of Renal impairment have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.5% of all adverse event reports for IRINOTECAN.
135
Reports of Renal impairment with IRINOTECAN
0.5%
of all IRINOTECAN reports
20
Deaths
37
Hospitalizations
How Dangerous Is Renal impairment From IRINOTECAN?
Of the 135 reports, 20 (14.8%) resulted in death, 37 (27.4%) required hospitalization, and 6 (4.4%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 135 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which IRINOTECAN Alternatives Have Lower Renal impairment Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE