Does ISOFLURANE Cause Multiple-drug resistance? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Multiple-drug resistance have been filed in association with ISOFLURANE (Isoflurane). This represents 4.0% of all adverse event reports for ISOFLURANE.
33
Reports of Multiple-drug resistance with ISOFLURANE
4.0%
of all ISOFLURANE reports
29
Deaths
23
Hospitalizations
How Dangerous Is Multiple-drug resistance From ISOFLURANE?
Of the 33 reports, 29 (87.9%) resulted in death, 23 (69.7%) required hospitalization, and 22 (66.7%) were considered life-threatening.
Is Multiple-drug resistance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISOFLURANE. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does ISOFLURANE Cause?
Drug ineffective (134)
Hypotension (127)
Off label use (90)
Hyperthermia malignant (87)
Intestinal ischaemia (77)
Status epilepticus (75)
Systemic inflammatory response syndrome (63)
Necrosis ischaemic (56)
Post procedural complication (55)
Metabolic acidosis (54)
What Other Drugs Cause Multiple-drug resistance?
LEVETIRACETAM (1,378)
LACOSAMIDE (739)
VALPROIC ACID (622)
TOPIRAMATE (521)
CLOBAZAM (486)
LAMOTRIGINE (418)
PHENOBARBITAL (406)
PHENYTOIN (337)
CARBAMAZEPINE (299)
PERAMPANEL (258)
Which ISOFLURANE Alternatives Have Lower Multiple-drug resistance Risk?
ISOFLURANE vs ISONIAZID
ISOFLURANE vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISOFLURANE vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISOFLURANE vs ISONIAZID\RIFAMPIN
ISOFLURANE vs ISOPROPANOLAMINE