Does ISONIAZID Cause Clostridium difficile colitis? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Clostridium difficile colitis have been filed in association with ISONIAZID (Isoniazid). This represents 0.4% of all adverse event reports for ISONIAZID.
29
Reports of Clostridium difficile colitis with ISONIAZID
0.4%
of all ISONIAZID reports
17
Deaths
26
Hospitalizations
How Dangerous Is Clostridium difficile colitis From ISONIAZID?
Of the 29 reports, 17 (58.6%) resulted in death, 26 (89.7%) required hospitalization, and 12 (41.4%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which ISONIAZID Alternatives Have Lower Clostridium difficile colitis Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL