Does ISONIAZID Cause Pruritus? 150 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 150 reports of Pruritus have been filed in association with ISONIAZID (Isoniazid). This represents 2.0% of all adverse event reports for ISONIAZID.
150
Reports of Pruritus with ISONIAZID
2.0%
of all ISONIAZID reports
14
Deaths
77
Hospitalizations
How Dangerous Is Pruritus From ISONIAZID?
Of the 150 reports, 14 (9.3%) resulted in death, 77 (51.3%) required hospitalization, and 7 (4.7%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 150 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which ISONIAZID Alternatives Have Lower Pruritus Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL