Does ISONIAZID\PYRAZINAMIDE\RIFAMPIN Cause Hepatitis? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Hepatitis have been filed in association with ISONIAZID\PYRAZINAMIDE\RIFAMPIN. This represents 2.7% of all adverse event reports for ISONIAZID\PYRAZINAMIDE\RIFAMPIN.
11
Reports of Hepatitis with ISONIAZID\PYRAZINAMIDE\RIFAMPIN
2.7%
of all ISONIAZID\PYRAZINAMIDE\RIFAMPIN reports
0
Deaths
10
Hospitalizations
How Dangerous Is Hepatitis From ISONIAZID\PYRAZINAMIDE\RIFAMPIN?
Of the 11 reports, 10 (90.9%) required hospitalization.
Is Hepatitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID\PYRAZINAMIDE\RIFAMPIN. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID\PYRAZINAMIDE\RIFAMPIN Cause?
Hepatic cytolysis (50)
Drug reaction with eosinophilia and systemic symptoms (39)
Hepatocellular injury (37)
Cholestasis (32)
Thrombocytopenia (20)
Rash maculo-papular (19)
Rash (17)
Pyrexia (16)
Jaundice (15)
Pruritus (15)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which ISONIAZID\PYRAZINAMIDE\RIFAMPIN Alternatives Have Lower Hepatitis Risk?
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISONIAZID\RIFAMPIN
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISOPROPANOLAMINE
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISOPROPYL ALCOHOL
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISOPROPYL ALCOHOL\LEUPROLIDE