Does IVABRADINE Cause Hepatic failure? 6 Reports in FDA Database

Q: Does IVABRADINE cause Hepatic failure?

6 reports of Hepatic failure have been filed with the FDA for IVABRADINE, representing 0.1% of all IVABRADINE adverse event reports.

Q: How dangerous is Hepatic failure from IVABRADINE?

Of 6 reports, 2 (33.3%) resulted in death and 4 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Hepatic failure have been filed in association with IVABRADINE (IVABRADINE). This represents 0.1% of all adverse event reports for IVABRADINE.

Reports of Hepatic failure with IVABRADINE

0.1%

of all IVABRADINE reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From IVABRADINE?

Of the 6 reports, 2 (33.3%) resulted in death, 4 (66.7%) required hospitalization, and 1 (16.7%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for IVABRADINE. However, 6 reports have been filed with the FAERS database.

What Other Side Effects Does IVABRADINE Cause?

Off label use (1,218) Dyspnoea (304) Bradycardia (295) Hypotension (290) Cardiac failure (270) Dizziness (240) Drug ineffective (185) Chest pain (162) Fatigue (156) Palpitations (138)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which IVABRADINE Alternatives Have Lower Hepatic failure Risk?

IVABRADINE vs IVACAFTOR IVABRADINE vs IVACAFTOR\LUMACAFTOR IVABRADINE vs IVACAFTOR\TEZACAFTOR IVABRADINE vs IVERMECTIN IVABRADINE vs IVOSIDENIB

IVABRADINE Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure IVABRADINE Demographics