Does LAMOTRIGINE Cause Encephalopathy? 204 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 204 reports of Encephalopathy have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.4% of all adverse event reports for LAMOTRIGINE.
204
Reports of Encephalopathy with LAMOTRIGINE
0.4%
of all LAMOTRIGINE reports
8
Deaths
144
Hospitalizations
How Dangerous Is Encephalopathy From LAMOTRIGINE?
Of the 204 reports, 8 (3.9%) resulted in death, 144 (70.6%) required hospitalization, and 43 (21.1%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 204 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which LAMOTRIGINE Alternatives Have Lower Encephalopathy Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM