Does LAMOTRIGINE Cause Hypernatraemia? 90 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 90 reports of Hypernatraemia have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.2% of all adverse event reports for LAMOTRIGINE.
90
Reports of Hypernatraemia with LAMOTRIGINE
0.2%
of all LAMOTRIGINE reports
13
Deaths
75
Hospitalizations
How Dangerous Is Hypernatraemia From LAMOTRIGINE?
Of the 90 reports, 13 (14.4%) resulted in death, 75 (83.3%) required hospitalization, and 42 (46.7%) were considered life-threatening.
Is Hypernatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 90 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Hypernatraemia?
TOLVAPTAN (235)
FUROSEMIDE (192)
LITHIUM (186)
SODIUM (136)
VALPROIC ACID (88)
OLANZAPINE (87)
METFORMIN (79)
QUETIAPINE (77)
ARIPIPRAZOLE (69)
DAPAGLIFLOZIN (67)
Which LAMOTRIGINE Alternatives Have Lower Hypernatraemia Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM