Does VALPROIC ACID Cause Hypernatraemia? 88 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 88 reports of Hypernatraemia have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.4% of all adverse event reports for VALPROIC ACID.
88
Reports of Hypernatraemia with VALPROIC ACID
0.4%
of all VALPROIC ACID reports
10
Deaths
73
Hospitalizations
How Dangerous Is Hypernatraemia From VALPROIC ACID?
Of the 88 reports, 10 (11.4%) resulted in death, 73 (83.0%) required hospitalization, and 36 (40.9%) were considered life-threatening.
Is Hypernatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 88 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Hypernatraemia?
TOLVAPTAN (235)
FUROSEMIDE (192)
LITHIUM (186)
SODIUM (136)
LAMOTRIGINE (90)
OLANZAPINE (87)
METFORMIN (79)
QUETIAPINE (77)
ARIPIPRAZOLE (69)
DAPAGLIFLOZIN (67)
Which VALPROIC ACID Alternatives Have Lower Hypernatraemia Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN