Does TOLVAPTAN Cause Hypernatraemia? 235 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 235 reports of Hypernatraemia have been filed in association with TOLVAPTAN (Jynarque). This represents 2.6% of all adverse event reports for TOLVAPTAN.
235
Reports of Hypernatraemia with TOLVAPTAN
2.6%
of all TOLVAPTAN reports
89
Deaths
76
Hospitalizations
How Dangerous Is Hypernatraemia From TOLVAPTAN?
Of the 235 reports, 89 (37.9%) resulted in death, 76 (32.3%) required hospitalization, and 34 (14.5%) were considered life-threatening.
Is Hypernatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOLVAPTAN. However, 235 reports have been filed with the FAERS database.
What Other Side Effects Does TOLVAPTAN Cause?
Death (800)
Thirst (624)
Off label use (560)
Renal impairment (534)
Underdose (448)
Product use in unapproved indication (446)
Wrong technique in product usage process (426)
Polyuria (390)
Product dose omission issue (379)
Inappropriate schedule of product administration (376)
What Other Drugs Cause Hypernatraemia?
FUROSEMIDE (192)
LITHIUM (186)
SODIUM (136)
LAMOTRIGINE (90)
VALPROIC ACID (88)
OLANZAPINE (87)
METFORMIN (79)
QUETIAPINE (77)
ARIPIPRAZOLE (69)
DAPAGLIFLOZIN (67)
Which TOLVAPTAN Alternatives Have Lower Hypernatraemia Risk?
TOLVAPTAN vs TOPAMAX
TOLVAPTAN vs TOPIRAMATE
TOLVAPTAN vs TOPOTECAN
TOLVAPTAN vs TOPOTECAN\TOPOTECAN
TOLVAPTAN vs TOPROL