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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Hypernatraemia: Which Medications Cause It? (3,351 Reports Across 323 Drugs)

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Hypernatraemia has been reported as an adverse event with 323 different drugs in the FDA's FAERS database, with 3,351 total reports. 723 of these reports resulted in death.The drugs most commonly associated with Hypernatraemia are TOLVAPTAN, FUROSEMIDE, and LITHIUM.

3,351
Total Reports
323
Drugs Involved
723
Deaths
2,279
Hospitalizations
57.0 yrs
Average Patient Age
50.3% / 49.7%
Female / Male

Which Drugs Cause Hypernatraemia Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
TOLVAPTAN 235 2.6% 89 76 34
FUROSEMIDE 192 0.4% 45 124 24
LITHIUM 186 1.2% 22 132 26
SODIUM 136 0.6% 24 87 22
LAMOTRIGINE 90 0.2% 13 75 42
VALPROIC ACID 88 0.4% 10 73 36
OLANZAPINE 87 0.2% 10 71 26
METFORMIN 79 0.1% 2 61 15
QUETIAPINE 77 0.1% 17 64 15
ARIPIPRAZOLE 69 0.1% 5 59 24
DAPAGLIFLOZIN 67 0.3% 5 52 7
METHOTREXATE 64 0.0% 21 46 23
PREDNISONE 64 0.0% 8 51 19
CLOZAPINE 63 0.1% 10 51 5
SERTRALINE 63 0.1% 3 63 24
DESMOPRESSIN 62 1.6% 1 44 4
EMPAGLIFLOZIN 62 0.2% 2 38 14
DEXAMETHASONE 61 0.1% 18 48 7
PIPERACILLIN\TAZOBACTAM 57 0.3% 11 30 16
VALPROATE 56 0.4% 8 42 10

View all 323 drugs →

Top 3 Drugs Associated With Hypernatraemia

235 reports
192 reports
186 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)