Does VALPROATE Cause Hypernatraemia? 56 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 56 reports of Hypernatraemia have been filed in association with VALPROATE (Valproate Sodium). This represents 0.4% of all adverse event reports for VALPROATE.
56
Reports of Hypernatraemia with VALPROATE
0.4%
of all VALPROATE reports
8
Deaths
42
Hospitalizations
How Dangerous Is Hypernatraemia From VALPROATE?
Of the 56 reports, 8 (14.3%) resulted in death, 42 (75.0%) required hospitalization, and 10 (17.9%) were considered life-threatening.
Is Hypernatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROATE. However, 56 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROATE Cause?
Foetal exposure during pregnancy (1,982)
Drug ineffective (1,268)
Seizure (1,083)
Epilepsy (878)
Somnolence (843)
Off label use (744)
Drug abuse (705)
Sopor (577)
Dysmorphism (552)
Drug interaction (513)
What Other Drugs Cause Hypernatraemia?
TOLVAPTAN (235)
FUROSEMIDE (192)
LITHIUM (186)
SODIUM (136)
LAMOTRIGINE (90)
VALPROIC ACID (88)
OLANZAPINE (87)
METFORMIN (79)
QUETIAPINE (77)
ARIPIPRAZOLE (69)
Which VALPROATE Alternatives Have Lower Hypernatraemia Risk?
VALPROATE vs VALPROIC ACID
VALPROATE vs VALPROMIDE
VALPROATE vs VALSARTAN
VALPROATE vs VALTREX
VALPROATE vs VAMOROLONE