Does CLOZAPINE Cause Hypernatraemia? 63 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 63 reports of Hypernatraemia have been filed in association with CLOZAPINE (CLOZAPINE). This represents 0.1% of all adverse event reports for CLOZAPINE.
63
Reports of Hypernatraemia with CLOZAPINE
0.1%
of all CLOZAPINE reports
10
Deaths
51
Hospitalizations
How Dangerous Is Hypernatraemia From CLOZAPINE?
Of the 63 reports, 10 (15.9%) resulted in death, 51 (81.0%) required hospitalization, and 5 (7.9%) were considered life-threatening.
Is Hypernatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOZAPINE. However, 63 reports have been filed with the FAERS database.
What Other Side Effects Does CLOZAPINE Cause?
Neutropenia (18,981)
Hospitalisation (12,144)
Death (9,500)
Schizophrenia (3,991)
White blood cell count decreased (3,454)
Off label use (3,192)
Neutrophil count increased (3,125)
Drug ineffective (3,105)
Neutrophilia (3,105)
White blood cell count increased (2,988)
What Other Drugs Cause Hypernatraemia?
TOLVAPTAN (235)
FUROSEMIDE (192)
LITHIUM (186)
SODIUM (136)
LAMOTRIGINE (90)
VALPROIC ACID (88)
OLANZAPINE (87)
METFORMIN (79)
QUETIAPINE (77)
ARIPIPRAZOLE (69)
Which CLOZAPINE Alternatives Have Lower Hypernatraemia Risk?
CLOZAPINE vs CLOZARIL
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL