Does LEFLUNOMIDE Cause Encephalopathy? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Encephalopathy have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 0.1% of all adverse event reports for LEFLUNOMIDE.
55
Reports of Encephalopathy with LEFLUNOMIDE
0.1%
of all LEFLUNOMIDE reports
39
Deaths
49
Hospitalizations
How Dangerous Is Encephalopathy From LEFLUNOMIDE?
Of the 55 reports, 39 (70.9%) resulted in death, 49 (89.1%) required hospitalization, and 33 (60.0%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which LEFLUNOMIDE Alternatives Have Lower Encephalopathy Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM