Does LEFLUNOMIDE Cause Exostosis? 743 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 743 reports of Exostosis have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 1.3% of all adverse event reports for LEFLUNOMIDE.
743
Reports of Exostosis with LEFLUNOMIDE
1.3%
of all LEFLUNOMIDE reports
364
Deaths
435
Hospitalizations
How Dangerous Is Exostosis From LEFLUNOMIDE?
Of the 743 reports, 364 (49.0%) resulted in death, 435 (58.5%) required hospitalization, and 350 (47.1%) were considered life-threatening.
Is Exostosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 743 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Exostosis?
ADALIMUMAB (2,008)
METHOTREXATE (968)
ETANERCEPT (918)
ABATACEPT (775)
TOCILIZUMAB (768)
SULFASALAZINE (712)
DICLOFENAC (702)
TOFACITINIB (702)
CERTOLIZUMAB PEGOL (695)
ALENDRONATE (686)
Which LEFLUNOMIDE Alternatives Have Lower Exostosis Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM