Does TOCILIZUMAB Cause Exostosis? 768 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 768 reports of Exostosis have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 0.8% of all adverse event reports for TOCILIZUMAB.
768
Reports of Exostosis with TOCILIZUMAB
0.8%
of all TOCILIZUMAB reports
455
Deaths
446
Hospitalizations
How Dangerous Is Exostosis From TOCILIZUMAB?
Of the 768 reports, 455 (59.2%) resulted in death, 446 (58.1%) required hospitalization, and 338 (44.0%) were considered life-threatening.
Is Exostosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOCILIZUMAB. However, 768 reports have been filed with the FAERS database.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Exostosis?
ADALIMUMAB (2,008)
METHOTREXATE (968)
ETANERCEPT (918)
ABATACEPT (775)
LEFLUNOMIDE (743)
SULFASALAZINE (712)
DICLOFENAC (702)
TOFACITINIB (702)
CERTOLIZUMAB PEGOL (695)
ALENDRONATE (686)
Which TOCILIZUMAB Alternatives Have Lower Exostosis Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE