Does TOFACITINIB Cause Exostosis? 702 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 702 reports of Exostosis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.5% of all adverse event reports for TOFACITINIB.
702
Reports of Exostosis with TOFACITINIB
0.5%
of all TOFACITINIB reports
333
Deaths
316
Hospitalizations
How Dangerous Is Exostosis From TOFACITINIB?
Of the 702 reports, 333 (47.4%) resulted in death, 316 (45.0%) required hospitalization, and 275 (39.2%) were considered life-threatening.
Is Exostosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 702 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Exostosis?
ADALIMUMAB (2,008)
METHOTREXATE (968)
ETANERCEPT (918)
ABATACEPT (775)
TOCILIZUMAB (768)
LEFLUNOMIDE (743)
SULFASALAZINE (712)
DICLOFENAC (702)
CERTOLIZUMAB PEGOL (695)
ALENDRONATE (686)
Which TOFACITINIB Alternatives Have Lower Exostosis Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN