Does LEFLUNOMIDE Cause Hepatic failure? 70 Reports in FDA Database

Q: Does LEFLUNOMIDE cause Hepatic failure?

70 reports of Hepatic failure have been filed with the FDA for LEFLUNOMIDE, representing 0.1% of all LEFLUNOMIDE adverse event reports.

Q: How dangerous is Hepatic failure from LEFLUNOMIDE?

Of 70 reports, 44 (62.9%) resulted in death and 42 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 70 reports of Hepatic failure have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 0.1% of all adverse event reports for LEFLUNOMIDE.

Reports of Hepatic failure with LEFLUNOMIDE

0.1%

of all LEFLUNOMIDE reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From LEFLUNOMIDE?

Of the 70 reports, 44 (62.9%) resulted in death, 42 (60.0%) required hospitalization, and 29 (41.4%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for LEFLUNOMIDE.

What Other Side Effects Does LEFLUNOMIDE Cause?

Drug ineffective (31,396) Rheumatoid arthritis (20,886) Pain (15,594) Drug intolerance (14,142) Joint swelling (13,026) Fatigue (11,959) Arthralgia (11,880) Rash (11,239) Contraindicated product administered (11,206) Abdominal discomfort (10,333)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which LEFLUNOMIDE Alternatives Have Lower Hepatic failure Risk?

LEFLUNOMIDE vs LEMBOREXANT LEFLUNOMIDE vs LENACAPAVIR LEFLUNOMIDE vs LENALIDOMIDE LEFLUNOMIDE vs LENIOLISIB LEFLUNOMIDE vs LENOGRASTIM

LEFLUNOMIDE Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure LEFLUNOMIDE Demographics