Does LETROZOLE Cause Hepatic failure? 157 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 157 reports of Hepatic failure have been filed in association with LETROZOLE (Letrozole). This represents 0.5% of all adverse event reports for LETROZOLE.
157
Reports of Hepatic failure with LETROZOLE
0.5%
of all LETROZOLE reports
117
Deaths
96
Hospitalizations
How Dangerous Is Hepatic failure From LETROZOLE?
Of the 157 reports, 117 (74.5%) resulted in death, 96 (61.1%) required hospitalization, and 30 (19.1%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 157 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which LETROZOLE Alternatives Have Lower Hepatic failure Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL