Does LETROZOLE Cause Osteonecrosis? 73 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 73 reports of Osteonecrosis have been filed in association with LETROZOLE (Letrozole). This represents 0.2% of all adverse event reports for LETROZOLE.
73
Reports of Osteonecrosis with LETROZOLE
0.2%
of all LETROZOLE reports
0
Deaths
22
Hospitalizations
How Dangerous Is Osteonecrosis From LETROZOLE?
Of the 73 reports, 22 (30.1%) required hospitalization, and 2 (2.7%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 73 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which LETROZOLE Alternatives Have Lower Osteonecrosis Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL