Does LEUCOVORIN Cause Hepatic failure? 120 Reports in FDA Database

Q: Does LEUCOVORIN cause Hepatic failure?

120 reports of Hepatic failure have been filed with the FDA for LEUCOVORIN, representing 0.5% of all LEUCOVORIN adverse event reports.

Q: How dangerous is Hepatic failure from LEUCOVORIN?

Of 120 reports, 91 (75.8%) resulted in death and 46 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 120 reports of Hepatic failure have been filed in association with LEUCOVORIN (LEUCOVORIN CALCIUM). This represents 0.5% of all adverse event reports for LEUCOVORIN.

120

Reports of Hepatic failure with LEUCOVORIN

0.5%

of all LEUCOVORIN reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From LEUCOVORIN?

Of the 120 reports, 91 (75.8%) resulted in death, 46 (38.3%) required hospitalization, and 26 (21.7%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for LEUCOVORIN. However, 120 reports have been filed with the FAERS database.

What Other Side Effects Does LEUCOVORIN Cause?

Diarrhoea (2,594) Neutropenia (2,291) Nausea (1,977) Neuropathy peripheral (1,557) Disease progression (1,456) Fatigue (1,443) Vomiting (1,441) Off label use (1,390) Thrombocytopenia (1,181) Pyrexia (1,148)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which LEUCOVORIN Alternatives Have Lower Hepatic failure Risk?

LEUCOVORIN vs LEUCOVORIN\LEUCOVORIN LEUCOVORIN vs LEUPROLIDE LEUCOVORIN vs LEVALBUTEROL LEUCOVORIN vs LEVAMISOLE LEUCOVORIN vs LEVAQUIN

LEUCOVORIN Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure LEUCOVORIN Demographics