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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does LEUCOVORIN Cause Osteonecrosis? 35 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Osteonecrosis have been filed in association with LEUCOVORIN (LEUCOVORIN CALCIUM). This represents 0.1% of all adverse event reports for LEUCOVORIN.

35
Reports of Osteonecrosis with LEUCOVORIN
0.1%
of all LEUCOVORIN reports
5
Deaths
14
Hospitalizations

How Dangerous Is Osteonecrosis From LEUCOVORIN?

Of the 35 reports, 5 (14.3%) resulted in death, 14 (40.0%) required hospitalization, and 2 (5.7%) were considered life-threatening.

Is Osteonecrosis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for LEUCOVORIN. However, 35 reports have been filed with the FAERS database.

What Other Side Effects Does LEUCOVORIN Cause?

Diarrhoea (2,594) Neutropenia (2,291) Nausea (1,977) Neuropathy peripheral (1,557) Disease progression (1,456) Fatigue (1,443) Vomiting (1,441) Off label use (1,390) Thrombocytopenia (1,181) Pyrexia (1,148)

What Other Drugs Cause Osteonecrosis?

EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935) TENOFOVIR DISOPROXIL (7,182) EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338) COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081) EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492) PREDNISONE (779) PREDNISOLONE (711) DENOSUMAB (567) METHOTREXATE (563) DEXAMETHASONE (531)

Which LEUCOVORIN Alternatives Have Lower Osteonecrosis Risk?

LEUCOVORIN vs LEUCOVORIN\LEUCOVORIN LEUCOVORIN vs LEUPROLIDE LEUCOVORIN vs LEVALBUTEROL LEUCOVORIN vs LEVAMISOLE LEUCOVORIN vs LEVAQUIN

Related Pages

LEUCOVORIN Full Profile All Osteonecrosis Reports All Drugs Causing Osteonecrosis LEUCOVORIN Demographics