Does LEVOLEUCOVORIN Cause Encephalopathy? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Encephalopathy have been filed in association with LEVOLEUCOVORIN (Levoleucovorin). This represents 0.5% of all adverse event reports for LEVOLEUCOVORIN.
15
Reports of Encephalopathy with LEVOLEUCOVORIN
0.5%
of all LEVOLEUCOVORIN reports
2
Deaths
8
Hospitalizations
How Dangerous Is Encephalopathy From LEVOLEUCOVORIN?
Of the 15 reports, 2 (13.3%) resulted in death, 8 (53.3%) required hospitalization, and 3 (20.0%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEVOLEUCOVORIN. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does LEVOLEUCOVORIN Cause?
Diarrhoea (302)
Nausea (274)
Neutropenia (246)
Decreased appetite (223)
Neuropathy peripheral (178)
Neutrophil count decreased (176)
Pyrexia (175)
Vomiting (167)
Febrile neutropenia (130)
Off label use (125)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which LEVOLEUCOVORIN Alternatives Have Lower Encephalopathy Risk?
LEVOLEUCOVORIN vs LEVOMEPROMAZINE
LEVOLEUCOVORIN vs LEVOMETHADONE
LEVOLEUCOVORIN vs LEVOMILNACIPRAN
LEVOLEUCOVORIN vs LEVONORGESTREL
LEVOLEUCOVORIN vs LEVORPHANOL