Does LOPINAVIR\RITONAVIR Cause Osteonecrosis? 133 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 133 reports of Osteonecrosis have been filed in association with LOPINAVIR\RITONAVIR. This represents 1.6% of all adverse event reports for LOPINAVIR\RITONAVIR.
133
Reports of Osteonecrosis with LOPINAVIR\RITONAVIR
1.6%
of all LOPINAVIR\RITONAVIR reports
1
Deaths
19
Hospitalizations
How Dangerous Is Osteonecrosis From LOPINAVIR\RITONAVIR?
Of the 133 reports, 1 (0.8%) resulted in death, 19 (14.3%) required hospitalization.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LOPINAVIR\RITONAVIR. However, 133 reports have been filed with the FAERS database.
What Other Side Effects Does LOPINAVIR\RITONAVIR Cause?
Off label use (2,010)
Foetal exposure during pregnancy (932)
Drug interaction (821)
Depression (551)
Virologic failure (428)
Exposure during pregnancy (395)
Diarrhoea (363)
Maternal exposure during pregnancy (311)
Product use in unapproved indication (282)
Nausea (243)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which LOPINAVIR\RITONAVIR Alternatives Have Lower Osteonecrosis Risk?
LOPINAVIR\RITONAVIR vs LOPRAZOLAM
LOPINAVIR\RITONAVIR vs LORATADINE
LOPINAVIR\RITONAVIR vs LORATADINE\PSEUDOEPHEDRINE
LOPINAVIR\RITONAVIR vs LORAZEPAM
LOPINAVIR\RITONAVIR vs LORCASERIN